Women’s Health Fund IV
This fund continues to accept larger-scale investments through the end of the year. Connect with Investor Relations to learn about remaining access — and what’s coming next from Portfolia soon.
Why Invest In Women’s Health?
$600B+ Market
Women's health is one of the largest, fastest-growing opportunities in healthcare — yet receives less than 5% of research funding.
Chronically Underfunded
Women make 80% of healthcare decisions, yet receive less than 2% of venture capital funding.
Early-Stage Advantage
Over 50% of women's health conditions remain without an FDA-approved treatment — the innovation pipeline is just getting started.
Invest With a Community That Is Changing the Future
At Portfolia, we believe investing is more impactful—and more rewarding—when you do it together. Our members are entrepreneurs, executives, innovators, and changemakers, united by a shared vision: to invest in breakthrough innovations that deliver both strong returns and lasting impact.
What Makes Our Approach Different:
Powerful Member Network
Exceptional Companies, Returned Focus
Broad Stage & Geographic Reach
World Class Fund Partners
Women's Health Fund IV Is Backing Breakthroughs
Gameto
An ovary in a petri dish enabling faster, cheaper and more reliable IVF
YourChoice
First male birth control pill.
Attn: Grace
Sustainable wellness brand designed for women
Hera Biotech
Early diagnosis & treatment for endometriosis
Lighthouse Pharma
Once-daily pill targeting a driver of Alzheimer's
X-Therma
Bio-preservation technology that extends the storage life of cells, tissues, and donor organs
ChronicleBio
Early diagnosis & treatment for auto-immune diseases
Flow
Medical technology company developing a novel, data-enabled catheter system
Osteoboost
First FDA-cleared wearable device to help preserve bone density.
FemDex
Medical devices that enable more accurate diagnosis of gynecological conditions and reproductive health.
Adjuvia Therapeutics
Oral nanoparticle therapies that target mitochondrial dysfunction to treat rare and degenerative diseases
Ready to Learn More About Investing With Porfolia?
Join us for one of our upcoming events. We’ll explore how easy it is to invest for returns + impact, the landscape of opportunities in women’s health and beyond, and answer your questions live.
JOIN USThese sessions are designed for prospective investors. If you're an entrepreneur seeking funding, feel free to join an upcoming Funding Info Session designed for founders who are currently fundraising. Click here to register.
The Partners
Led by Experts in Women’s Health and Venture Capital. Backed by decades of experience, our fund advisors source and vet opportunities with scientific rigor and strategic vision. Portfolia Partners are selected to join a fund because of their expertise and investment history in the relevant space, deep networks of co-investors and entrepreneurs, and their ability to add value to portfolio companies over the life of the investment. Fund Partners are best-in-class investors, with an average of 15+ years of investing experience.
Trish Costello
Founder and CEO of Portfolia
Nola Masterson
A biotech pioneer with 45+ years of experience, Nola was the first biotech analyst on Wall Street and co-founded Sequenom, Inc. She has launched and advised numerous life sciences companies and served on multiple public and private boards. A long-time Portfolia leader, she brings deep venture expertise, board governance, and a global leadership perspective to Women’s Health investing.
Faz K. Bashi, MD
Dr. Faz Bashi is a leader in life sciences investing with a background in immunology and virology. He has chaired multiple angel screening committees, led investments for Portfolia’s FemTech funds, and supports women entrepreneurs through Springboard Enterprises. He is a passionate advocate for innovation in diagnostics, digital health, and inclusive venture funding.
Sonia Arrison
Sonia Arrison is a longevity investor, author of 100 Plus, and founder of 100 Plus Capital. She serves on boards like the Foresight Institute and Alliance for Longevity Initiatives, and advises Felicis Ventures. A leader at the intersection of tech and aging, Sonia brings deep expertise in life extension, societal innovation, and investing in transformative aging solutions.
Jennifer Fried
CEO and co-founder of Flow Medical
Proven Track Record
Global leadership, optimized returns.
Talent that delivers.
Broad-based investment.
Investment Focus
- Women-specific Conditions: Contraception, Fertility, Maternal Health, Menopause, Gynecology & Women’s Oncology
- Conditions that Affect Women Differently: Cardiovascular Disease, Diabetes, Alzheimer’s Disease
- Conditions that Affect Women Disproportionally: Autoimmune Disease, Osteoporosis, Anxiety and Depression, Lung Cancer, Eating Disorders
FAQs
- Active Aging & Longevity Fund I is currently at 1.19x TVPI (Multiple) with a Projected TVPI of 2.81x
- FemTech Fund I is currently at .91x TVPI with a projected TVPI of 2.81x
- Active Aging & Longevity Fund II is currently at 1.05x TVPI with a projected TVPI of 3.68x.
- FemTech Fund II is currently at a .75x with a Projected TVPI of 2.57x
Portfolia is the recognized leader in the women's health sector and the most active investor globally in women’s health with 44 women’s health companies in its portfolio and has invested in 66 healthcare companies across all Portfolia funds.
The current portfolio of women’s health companies is strong, innovative, and scaling. Building on history, reputation and momentum, Portfolia commands a robust pipeline with unique deal flow and singular expertise in the marketplace, translating into growing opportunities in women's health and longevity, across all stages.
Portfolia investments include:
- Maven Clinic – $1.7B global virtual clinic for women
- Everly Health – $3B+ diagnostics-driven care through at-home lab tests
- Mirvie – RNA platform for early detection of preeclampsia
- Lighthouse Pharma – Breakthrough solutions for Dementia/Alzheimers
- Frontier Bio – Developing lab-grown human tissue
- Mercy Bioanalytics – Blood test for early detection of ovarian cancer
- Bone Health – The first FDA approved solution for osteopenia
- YourChoice – First non-hormonal male birth control pill
- Hera Biotech – Non-invasive diagnostic for endometriosis and cervical cancer
- Gameto – Breakthrough cell engineering targeting infertility and menopause
Women’s Health Fund Portfolia Partners are selected to join a fund because of their expertise and investment history in the relevant space, deep networks of co-investors and entrepreneurs, and their ability to add value to portfolio companies over the life of the investment. Fund Partners are best-in-class investors, with an average of 15+ years of investing experience.
Women’s Health IV Fund Partners:
- Trish Costello - Managing Director
- Nola Elizabeth Masterson, MSc. (FemTech I, II & III)
- Faz K. Bashi, MD (FemTech I, II & III)
- Jennifer Fried, M.B.A (FemTech I, II & III)
- Sonia Arrison (Active Aging II)
Fund Partners are geographically located in every major innovation hub in the US.
- Portfolia Women’s Health Fund IV is the next evolution in its proven, category-defining investment strategy backing high-growth, high-impact innovations that are transforming the health and wellness of women across every stage of life.
- Building on five successful prior funds in FemTech and Active Aging, Fund IV will invest in the most promising early to growth-stage companies at the intersection of science, technology, and female biology.
- Women make up half the population, control 80% of healthcare decisions, and account for over $15 trillion in global spending power, yet only 2% of venture funding in healthcare goes toward solutions built for their unique needs. Portfolia is here to change that.
- Portfolia provides the back office, structure and limited partner support so the world's top VCs can focus on investing.
- Portfolia's 46 partners across 15 funds lead the industry's best practices and provide an expert investing network across the industry.
- Portfolia's 2,000+ limited partners, across all 50 states and 20 countries, provide unparalleled knowledge, networks, and expertise.
Lead the Next Wave in Women’s Health
Portfolia’s
Women’s Health Fund IVhas reached full capacity for standard investment — a strong signal of the momentum behind breakthrough portfolio companies like Gameto and YourChoice. The fund continues to accept larger-scale investments through the end of the year.
to learn about remaining access — and what’s coming next from Portfolia this fall.
