Our Women’s Health Fund IV
is Now Open
Invest in the Future of Women’s Health
Shape the next era of care in fertility, diagnostics, menopause, mental health, longevity—and beyond.
An Unprecedented Market. An Unmatched Opportunity.
The women’s health market is a $1 trillion+ global opportunity—yet remains dramatically underfunded. From fertility to menopause to mental health, women deserve innovation. As an investor, you deserve access.
This is the fourth fund in Portfolia’s successful Women’s Health Series. With three previous funds already deployed, Portfolia has become the most active investor in women’s health globally. This next chapter builds on that momentum—offering early-stage access to the companies defining the future of care, aging, and wellness.
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Rising America Fund I, vintage 2020, is currently achieving a stunning gross TVPI of 3.20x and an IRR of 39.25%.
Rising America Fund II made is final investment Sept '24, and has a gross TVPI of 1.23x and an IRR of 13.29%.
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27 company investments in the portfolio – Pre-Seed to pre-IPO, across industry, geography
Led by the performance of a pre-seed investment in Canela Media, now valued at 40 times the original investment
56% of the portfolio have step-ups in valuations with nearly half of those at 3x or more, with one unicorn, Maven Clinic.
Industries include HealthTech, FinTech, Media, Enterprise, EdTech, and Beauty, Sports & Lifestyle
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Rising America Partners bring exception track records and investing expertise, with an average 16.4 years investing experience.
Rising America III Fund Partners:
Juliana Garaizar - Fund Partner
Sheila Collins - Fund Partner
Trish Costello - Fund Partner
Rising America III Fund Advisors:
Lorine Pendleton - Advisor
Karen Kerr - Advisor
Daphne Dufresne - Advisor
Rising America is the first venture capital fund to originally be led by 5 African American and Latina/Hispanic Women Partners.
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Proven Investing Thesis focused on an enormous, underserved market with rapidly growing economic power.
Unique deal flow across industry, stage, geography and demography.
World-Class Fund Partners uniquely positioned to provide outsized returns.
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Over 2,000 limited partners who are founders, visionaries and influencers from the US and globally
Deep Diligence Networks and Co-investing with Sequoia, General Catalist, Lux Capital, Ulu Ventures, True Ventures. 4 of 5 partners are Kauffman Fellows
Extensive innovation and organizational networks with Springboard, National Science Foundation, National Institutes of Health, Kauffman Fellows, VC Include, Toigo Fellowship and others.
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Portfolia provides the back office, structure and limited partner support so the world's top VCs can focus on investing.
Portfolia's 46 partners across 14 funds lead the industry's best practice, and provide an expert investing network across industry
Portfolia's 2,000 limited partner executive, across 48 states and 20 countries, provide unparalleled knowledge, networks, and expertise.
A WOMEN’S HEALTH FUND SUCCESS STORY
Maven is dedicated to closing gaps in care for women and families, prioritizing diversity, equity, and inclusion. They offer culturally competent care with specialists representing diverse backgrounds and speaking over 35 languages. They also actively invest in community-based organizations led by women working to improve health outcomes in their communities.
Maven Clinic becomes the first U.S. 'unicorn' dedicated to women's and family health, and Kate and Maven are just hitting their stride.
Maven Clinic is the largest virtual clinic dedicated to women's and family health.
Maven Clinic becomes the first U.S. 'unicorn' dedicated to women's and family health.
Maven partners with 2,000+ employers and health plans in 175+ countries to improve outcomes and promote benefits equity.
Founded by Kate Ryder in 2014, Maven has raised over $425M and is valued at $1.7 Billion following its Series F round in 2024.
Portfolia Member Investor?
Portfolia Member Investors can directly access the
investment documents via the Member Access portal:
Portfolia is the leading investor in women's health in the US, with 60+ investments in healthcare companies.
FUND PERFORMANCE
Portfolia is the most active investor in women's health in the US, with 60+ investments in fast-growth women’s health companies, from seed stage to pre-IPO. Investments include early-stage companies like Bone Health(osteopenia) and Your Choice (the first male birth control pill) to fast scaling brand-name companies, like unicorns Everly Health and Maven Clinic. The Portfolia Women’s Health Fund IV builds on Portfolia’s global brand in women's health, optimizing returns and enhancing the health and wellness of women globally.
This success is not tied to a single outlier but reflects our ability to identify untapped talent, underrepresented founders, and overlooked markets, creating real, sustainable value. These performance metrics speak to the power of investing in companies driving both exceptional financial results and meaningful impact.
WOMEN’S HEALTH FUND I, II, & III PORTFOLIO
This remarkable success stems not from a single company but reflects the strength and execution of a well-founded thesis. The Rising America Fund III plans to continue supporting top early and growth-stage companies by investing in a sector and stage-agnostic manner.
Company Highlights
INVESTMENT DETAILS
Women’s Health Fund companies span across the US, from pre-seed to pre-IPO investment stage, with seed and series A representing the majority of its investments.
The portfolio has a balanced multi-industry focus. Healthcare represents its strongest focus, but with signficant investments in fintech, media, edtech, consumer, beauty and enterprise.
Investments in women’s health is a $1 trillion opportunity.
2024 is on pace to become a top three funding year for the women's health sector.
$435M Investments in non-fertility startups in 2023
This single quarter record shows a heartening shift in the long-held misconception that fertility and pregnancy are the sole focus of women’s health.
76% Of women’s health companies have a female founder
Women’s Health In The News
The Partners
Led by Experts in Women’s Health and Venture Capital. Backed by decades of experience, our fund advisors source and vet opportunities with scientific rigor and strategic vision.
An Unprecedented Market.
An Unmatched Opportunity.
This is the fourth fund in Portfolia’s successful Women’s Health Series. With three previous funds already deployed, Portfolia has become the most active investor in women’s health globally.
This next chapter builds on that momentum—offering early-stage access to the companies defining the future of care, aging, and wellness.
INVESTING THESIS:
A $1 TRILLION INVESTMENT OPPORTUNITY
Traditionally, women’s health investment and research has been woefully underfunded. This is rapidly changing, and Portfolia is leading the way. Less than 2% of federal medical research had been invested in women’s health and until quite recently, women were systematically left out of research protocols. Today an additional $1 Billion has been committed to women’s health research opening up new innovations and opportunities for investment.
Venture capitalists are the ones that ‘greenlight’ and fund the latest healthcare technologies post research, but because women make up only 2% of VC investing partners, women’s health investments were rarely understood or appreciated for potential returns or impact. Portfolia has changed this dynamic, aggregating tens of millions of dollars of women’s investment capital and focusing our dollars and expertise in the growth and success of these companies.
The result is outsized financial returns for women and better health and wellness for ourselves, our children, and generations to come. Investing is where change happens.
Our Focus Areas
Portfolia goes beyond, the obvious investments in menstrual care, fertility solutions and pregnancy care have received the most significant investments, into all facets of women's health and wellness at every stage of life. Portfolia will consider companies in the following areas, but not limited to:
Women-specific Conditions: Contraception, Fertility, Maternal Health, Menopause, Gynecology & Women’s Oncology
Conditions that Affect Women Differently: Cardiovascular Disease, Diabetes, Alzheimer’s Disease
Conditions that Affect Women Disproportionally: Autoimmune Disease, Osteoporosis, Anxiety and Depression, Lung Cancer, Eating Disorders
Conditions Characterized by Gender-based Discrepancies in care: Pain Management, Behavioral Health, Addiction
Racial disparities and inequities in women's health: Conditions that affect women of color differently, access to care, quality of care, lack of culturally competent care providers, systemic racism
Women’s Health Fund Investments
PORTFOLIA COMPETITIVE ADVANTAGE
Portfolia provides the back office, structure and limited partner support so the world's top VCs can focus on investing, across 14 funds and 14 special purpose vehicle investments.
Portfolia Partners: Its 46 partners across 14 funds lead the venture capital industry's best practice, and provide an expert investing network across industry.
Portfolia Members: Portfolia's 2,000 limited partner executives, across 48 states and 20 countries, provide unparalleled knowledge, networks, and expertise.
Portfolia Model: Portfolia’s proven model — activating the world’s best women venture capitalists in a special partnership to unleash the capital of sophisticated women and minority limited partners, to back the companies we want in the world for returns and impact — shows that exceptional returns can come from radically different models of investing.
Portfolia Investing Experience: Portfolia is based on the knowledge that bringing sophisticated women to the investing table, as members in a transparent and educational investing experience, makes our investing better, our companies stronger and builds a emerging investing ecosystem for the future.
